Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies.
Identifieur interne : 000086 ( Main/Exploration ); précédent : 000085; suivant : 000087Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies.
Auteurs : Nisreen M A. Okba ; Ivy Widjaja ; Wentao Li ; Corine H. Geurtsvankessel ; Elmoubasher A B A. Farag ; Mohammed Al-Hajri ; Wan Beom Park ; Myoung-Don Oh ; Chantal B E M. Reusken ; Marion P G. Koopmans ; Berend-Jan Bosch ; Bart L. HaagmansSource :
- Emerging infectious diseases [ 1080-6059 ] ; 2020.
Abstract
We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing antibody titers, proving their use for serologic confirmatory diagnosis of Middle East respiratory syndrome.
DOI: 10.3201/eid2605.190921
PubMed: 32150528
Affiliations:
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Okba</name></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name></author><author><name sortKey="Li, Wentao" sort="Li, Wentao" uniqKey="Li W" first="Wentao" last="Li">Wentao Li</name></author><author><name sortKey="Geurtsvankessel, Corine H" sort="Geurtsvankessel, Corine H" uniqKey="Geurtsvankessel C" first="Corine H" last="Geurtsvankessel">Corine H. Geurtsvankessel</name></author><author><name sortKey="Farag, Elmoubasher A B A" sort="Farag, Elmoubasher A B A" uniqKey="Farag E" first="Elmoubasher A B A" last="Farag">Elmoubasher A B A. Farag</name></author><author><name sortKey="Al Hajri, Mohammed" sort="Al Hajri, Mohammed" uniqKey="Al Hajri M" first="Mohammed" last="Al-Hajri">Mohammed Al-Hajri</name></author><author><name sortKey="Park, Wan Beom" sort="Park, Wan Beom" uniqKey="Park W" first="Wan Beom" last="Park">Wan Beom Park</name></author><author><name sortKey="Oh, Myoung Don" sort="Oh, Myoung Don" uniqKey="Oh M" first="Myoung-Don" last="Oh">Myoung-Don Oh</name></author><author><name sortKey="Reusken, Chantal B E M" sort="Reusken, Chantal B E M" uniqKey="Reusken C" first="Chantal B E M" last="Reusken">Chantal B E M. Reusken</name></author><author><name sortKey="Koopmans, Marion P G" sort="Koopmans, Marion P G" uniqKey="Koopmans M" first="Marion P G" last="Koopmans">Marion P G. Koopmans</name></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend-Jan" last="Bosch">Berend-Jan Bosch</name></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L" last="Haagmans">Bart L. Haagmans</name></author></analytic><series><title level="j">Emerging infectious diseases</title><idno type="eISSN">1080-6059</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing antibody titers, proving their use for serologic confirmatory diagnosis of Middle East respiratory syndrome.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Al Hajri, Mohammed" sort="Al Hajri, Mohammed" uniqKey="Al Hajri M" first="Mohammed" last="Al-Hajri">Mohammed Al-Hajri</name><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend-Jan" last="Bosch">Berend-Jan Bosch</name><name sortKey="Farag, Elmoubasher A B A" sort="Farag, Elmoubasher A B A" uniqKey="Farag E" first="Elmoubasher A B A" last="Farag">Elmoubasher A B A. Farag</name><name sortKey="Geurtsvankessel, Corine H" sort="Geurtsvankessel, Corine H" uniqKey="Geurtsvankessel C" first="Corine H" last="Geurtsvankessel">Corine H. Geurtsvankessel</name><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L" last="Haagmans">Bart L. Haagmans</name><name sortKey="Koopmans, Marion P G" sort="Koopmans, Marion P G" uniqKey="Koopmans M" first="Marion P G" last="Koopmans">Marion P G. Koopmans</name><name sortKey="Li, Wentao" sort="Li, Wentao" uniqKey="Li W" first="Wentao" last="Li">Wentao Li</name><name sortKey="Oh, Myoung Don" sort="Oh, Myoung Don" uniqKey="Oh M" first="Myoung-Don" last="Oh">Myoung-Don Oh</name><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M A" last="Okba">Nisreen M A. Okba</name><name sortKey="Park, Wan Beom" sort="Park, Wan Beom" uniqKey="Park W" first="Wan Beom" last="Park">Wan Beom Park</name><name sortKey="Reusken, Chantal B E M" sort="Reusken, Chantal B E M" uniqKey="Reusken C" first="Chantal B E M" last="Reusken">Chantal B E M. Reusken</name><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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